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PMC:3218875 JSONTXT

Divisions (14)
 

div. section text # proj. length # Ann.
0 TIAB Negative regulation of NF-κB and its involvement in rheumatoid arthritis The transcription factor NF 33 662 239 show
1 Introduction Rheumatoid arthritis (RA) is the most common inflammatory arthritis, affecting up to 1% of the adult 26 2362 1370 show
2 Pathological triggers of NF-κB signalling in RA Since NF-κB is central to the process of inflammation in RA, much research deals with the identifica 26 3886 2119 show
3 Basic principles of NF-κB signalling NF-κB proteins are sequestered in the cytoplasm as latent complexes by inhibitory proteins referred 26 5367 4589 show
4 Negative regulation of NF-κB signalling in RA Since NF-κB activation is so crucial to many cellular processes, a tight regulation of the NF-κB sig 26 1976 1035 show
5 Negative regulation of NF-κB signalling in RA A20 protein A20 (also known as TNFAIP3) is a ubiquitin-editing protein that negatively regulates NF- 26 4923 3129 show
6 Negative regulation of NF-κB signalling in RA A20-binding inhibitors of NF-κB ABIN-1, ABIN-2 and ABIN-3 (also known as TNIP-1, TNIP-2, and TNIP-3) 26 2370 1509 show
7 Negative regulation of NF-κB signalling in RA Cylindromatosis protein Cylindromatosis (CYLD) protein was originally identified as a tumour suppres 26 2096 1411 show
8 Negative regulation of NF-κB signalling in RA Single-immunoglobulin IL-1 receptor-related protein Single-immunoglobulin IL-1 receptor-related (SIG 26 1317 862 show
9 Negative regulation of NF-κB signalling in RA TNF receptor-associated factor 1 TRAF1 is a unique member of the TRAF protein family because it lack 26 1561 1022 show
10 Negative regulation of NF-κB signalling in RA microRNAs miRNAs are recently discovered regulators of gene expression and represent a class of nonc 26 2591 1612 show
11 Conclusions The NF-κB family of transcription factors plays crucial roles in the inflammatory processes in RA le 26 828 306 show
12 Caption-Figure 1 Canonical NF-κB signalling and negative regulators. Ligand engagement of specific membrane receptors 26 2184 2045 show
13 Caption-Figure 2 Noncanonical NF-κB signalling. CD40 and RANK can activate the noncanonical NF-κB pathway that is dep 26 1317 1272 show