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Divisions (21)
 

div. section text # proj. length # Ann.
0 TIAB Foxp3 Represses Retroviral Transcription by Targeting Both NF-κB and CREB Pathways Forkhead box (Fox 28 1568 993 show
1 Introduction Immunological tolerance to self-antigens is the result of the deletion of self-reactive T lymphocyte 21 3983 1902 show
2 Results Foxp3 Suppresses NF-κB Dependent Transcriptional Activation To ascertain the molecular mechanisms by 21 2292 1253 show
3 Results The Carboxyl-Terminal FKH Domain Is Not Required for Suppression of NF-κB Activation in T Cells To d 21 2299 1421 show
4 Results Foxp3 Suppresses HIV-1 Gene Expression in Part through Blocking Activation of NF-κB If Foxp3 functio 21 2010 969 show
5 Results The Transactivation Functions of HTLV-I Tax Are Suppressed by Foxp3 Previous studies by Bettelli and 21 4173 2422 show
6 Results Increased Foxp3 Protein Expression Is Associated with Low HTLV-I Proviral Load Since Foxp3 is expres 21 1303 734 show
7 Results CREB Is a Target for Transcriptional Repression by Foxp3 Although Foxp3 could down-regulate Tax-depe 21 3903 2433 show
8 Results Foxp3 Antagonizes CREB Transcriptional Activation by Disrupting Coactivator Recruitment Stimulation 21 2906 1849 show
9 Discussion In the present study, we show that Foxp3 functions as a potent repressor of NF-κB- and CREB-dependen 21 8592 4741 show
10 Materials and Methods Cell culture. HEK 293T cells were cultured in Dulbecco's modified Eagle medium (Invitrogen, Carlsbad 21 453 202 show
11 Materials and Methods Patients and cell preparation. PBMCs were prepared by centrifugation over Ficoll-Hypaque gradients ( 21 683 237 show
12 Materials and Methods Plasmids. Expression vectors encoding human Foxp3 (pCMV-Foxp3-IRES-EGFP) and human Foxp3 lacking the 21 1490 538 show
13 Materials and Methods Isolation of primary human CD4+ T cells. CD4+ T cells were isolated from cryopreserved healthy donor 21 362 180 show
14 Materials and Methods Transient expression and luciferase assays. HEK 293T cells were plated at a density of 5 × 105 cells 21 1650 685 show
15 Materials and Methods Foxp3 and HTLV-I Tax expression analysis by real-time RT-PCR. Real-time RT-PCR analysis of Foxp3 and 21 946 597 show
16 Materials and Methods Real-time PCR. Real-time PCR analysis of HTLV-I (Tax) proviral load was performed as previously desc 21 467 227 show
17 Materials and Methods Western blot analysis. HEK 293T cells were plated at a density of 5 × 105 cells/well in six-well cul 21 1966 863 show
18 Materials and Methods Transcription factor DNA-binding analysis (TF-ELISA). CREB-1 and ATF-2 DNA-binding activity was anal 21 1021 441 show
19 Materials and Methods Flow cytometric analysis of Foxp3 protein expression. Cryopreserved PBMCs from HAM/TSP patients or H 21 1212 588 show
20 Materials and Methods Statistical analyses. The Mann-Whitney U test was used to compare the data between patients with HAM 21 112 42 show