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PMC:1087494 JSONTXT

Divisions (18)
 

div. section text # proj. length # Ann.
0 TIAB Add-on topiramate reduces weight in overweight patients with affective disorders: a clinical case se 3 1917 451 show
1 Background Psychiatric patients who receive long-term mood-stabilizing agents can gain excess body weight [1-3] 3 7737 216 show
2 Background Patients Patients in our mood disorders clinic are seen in regular intervals for long-term maintenan 3 2484 545 show
3 Background Concomitant medication The nine treatment resistant/incomplete responder patients took combinations 3 611 166 show
4 Background Topiramate dosage Topiramate dose was increased in steps of 25–50 mg every one to two weeks. After s 3 630 167 show
5 Background Statistical analysis The level of statistical significance for weight loss at each time-point during 3 407 47 show
6 Results Weight changes Patients have received topiramate for between 6 months and one year by the time of wr 3 604 131 show
7 Results Side effects One patient (N 5) noticed thinning of her hair and stopped the topiramate after six mon 3 2037 409 show
8 Results Clinical changes We do not perform regular formal ratings of the mood of our patients. However we re 3 636 149 show
9 Discussion This is a naturalistic case-series and the absence of a placebo control group could have influenced 3 5541 114 show
10 Conclusion Topiramate appears a very useful drug for weight reduction in patients with bipolar disorders. The m 3 731 128 show
11 Conclusion Dose titration Topiramate dose should be increased gradually and in two-weekly intervals. 3 89 11 show
12 Conclusion Cognitive function Topiramate is known to cause neurocognitive side effects. Psychiatrists should mo 3 170 35 show
13 Conclusion Pregnancy As with most other mood-stabilizers (anticonvulsants and lithium), women who may become pr 3 196 33 show
14 Conclusion Adequate hydration Patients should be advised to ensure adequate hydration, especially if they are p 3 135 21 show
15 Pre-publication history The pre-publication history for this paper can be accessed here: 3 64 15 show
16 Caption-Table 1 Characteristics of the patients and changes of their weight during the study. Both individual and me 3 393 97 show
17 Caption-Figure 1 Weight changes in the patients described in the study. The day of treatment is on the x-axis. The da 3 296 80 show